The DUTCH Plus (Dried Urine Test for Comprehensive Hormones) provides advanced insights into hormone levels, hormone metabolism, and adrenal function. This innovative test combines dried urine and saliva sampling over a 24-hour period, giving a more detailed picture of hormone production, metabolism, and circadian rhythms than traditional blood tests.
About DUTCH PLUS
Key Features of the DUTCH Plus Test
The DUTCH Plus evaluates both sex and adrenal hormones—such as cortisol,
testosterone, and estrogen—and their metabolites. This combination allows healthcare providers to identify underlying imbalances that may contribute to symptoms like fatigue, weight gain, mood swings, and reproductive health issues.
It also includes:
- Saliva testing for real-time cortisol and cortisone patterns throughout the day,
providing insight into adrenal health. - Cortisol Awakening Response (CAR) measurement, which assesses stress
resilience and HPA (hypothalamic-pituitary-adrenal) axis function. - Organic Acids Test (OATs), which analyzes neurotransmitter metabolites,
nutritional markers, oxidative stress indicators, and melatonin, offering deeper insights into metabolic health and inflammation.
What the DUTCH Plus Measures
Urinary Hormone and Metabolite Testing:
- Progesterone Metabolites
a. α-Pregnanediol
b. β-Pregnanediol - Estrogens and Metabolites
a. Estrone (E1)
b. Estradiol (E2)
c. Estriol (E3)
d. 2-OH-E1, 4-OH-E1, 16-OH-E1
e. 2-Methoxy-E1, 2-OH-E2, 4-OH-E2 - Androgens and Metabolites
a. DHEA-S
b. Testosterone
c. 5α-DHT, 5α- and 5β-Androstanediol
d. Androsterone, Etiocholanolone - Cortisol and Cortisone Metabolites
5. a. α-THF, β-THF, β-Tetrahydrocortisone
b. Free Cortisol and Cortisone (Saliva) - Nutritional Organic Acids and Neuro-Related Markers
a. Vitamin B6/B12 Markers (e.g., Xanthurenate, Methylmalonate)
b. Gut Dysbiosis Marker: Indican
c. Dopamine & Norepinephrine Metabolites: HVA and VMA
d. Oxidative Stress: 8-OHdG - Melatonin (6-OH-Melatonin-Sulfate)
Why Test Sex Hormones and Their Metabolites?
Hormonal imbalances can affect everything from reproductive health to mood and metabolism. The DUTCH Plus provides a comprehensive view of estrogen, progesterone, and testosterone metabolites to detect conditions such as:
- Estrogen dominance: Linked to heavy periods, mood swings, and increased cancer risk.
- Estrogen deficiency: Common in menopause, with symptoms like hot flashes and insomnia.
- Testosterone imbalances: Can impact libido, muscle mass, and mood, with elevated levels associated with PCOS.
- Progesterone deficiency: Often related to irregular cycles, insomnia, and
infertility.
The test also evaluates how the body processes and eliminates estrogens through Phase 1 and Phase 2 detoxification pathways, critical for maintaining hormonal balance and reducing cancer risk.
Organic Acids Testing (OATs) Benefits
The organic acids component of the DUTCH Plus test provides:
- Neurotransmitter insights through markers like HVA and VMA, helping evaluate mental health and mood.
- B-vitamin status and oxidative stress markers, identifying potential nutritional deficiencies and inflammation.
- Gut health analysis through markers like Indican, which indicates dysbiosis, a factor in estrogen recirculation and overall hormone health.
Who Can Benefit from the DUTCH Plus Test?
This test is ideal for individuals experiencing:
- Hormone-related symptoms: Irregular periods, PCOS, infertility, or menopausal symptoms.
- Chronic stress, burnout, or adrenal fatigue.
- Mood disturbances: Anxiety, depression, or sleep issues.
- Weight management challenges due to hormonal imbalances or oxidative stress.
- Personalized health management: Individuals seeking customized interventions to optimize hormone balance and overall wellness.
It is also valuable for those undergoing hormone replacement therapy to monitor treatment efficacy and ensure proper hormone metabolism.
How to Get Started with the DUTCH Plus Test
- Book an appointment with a LivingYoung Wellness Provider to initiate the process.
- Receive the specialty test kit at home.
- Collect urine and saliva samples according to instructions.
- Schedule a blood sample collection with LivingYoung, and they will handle the shipping process.
Click here to view a sample of the DUTCH Plus Test.
The DUTCH Plus test offers a complete, non-invasive way to understand your hormonal and metabolic health, helping providers tailor personalized treatment plans for better outcomes and long-term well-being.
Pricing
$541
Initial Wellness Consultation
25 min $75
This is a great place to start if you are new to functional medicine therapies and are looking for a general overview on available treatment options. Available in person or via telemedicine.
50 min $150
This visit goes more in depth with our functional medicine practitioner. Based on your goals, she will guide you on the ideal testing and/or treatment options available to you.
Lab Evaluation
At this visit our functional medical practitioner will go over your lab results with you and make recommendations based on your results to optimize your health, including a customized treatment plan.
30 min $225 (Evaluate 1 test)
60 min $325 (Evaluate 2+ tests)
**Blood draw included at LivingYoung Center; additional fees may apply elsewhere.
**Lab prices subject to change.**
