When it comes to smoothing wrinkles, Botox isn’t the only game in town. Over the years, several FDA-approved neuromodulators have entered the market, including Xeomin, Daxxify, Jeuveau, and Dysport. All work on the same principle: they temporarily relax tiny facial muscles that create expression lines, allowing your skin to appear smoother and more refreshed. But they each have subtle differences in formulation, diffusion, and longevity that can make one option better suited for your unique goals.
Botox® Cosmetic
The gold standard and most recognized brand, Botox has been used safely for over two decades. Its active ingredient, onabotulinumtoxinA, is suspended in a protective protein complex. Botox’s precision and predictability make it ideal for first-time users or anyone seeking classic, reliable results.
Best for: Forehead lines, frown lines, crow’s feet, and beginners.
Onset: 5–10 days.
Duration: About 3–4 months.
Highlights: Unmatched track record and high patient satisfaction.
Xeomin®
Sometimes called the “naked” neuromodulator, Xeomin (incobotulinumtoxinA) is purified to remove accessory proteins. This means the body is less likely to form antibodies against it, a useful benefit for long-term users who may notice Botox becoming less effective over time. Clinically, Xeomin produces results nearly identical to Botox, with a smooth, natural finish.
Best for: Long-term users, sensitive individuals, or anyone concerned about resistance.
Onset: 3–7 days.
Duration: 3–4 months.
Highlights: Pure formulation; may lower risk of developing tolerance.
Daxxify®
The newest player in the field, Daxxify (daxibotulinumtoxinA-lanm) uses a unique peptide technology that allows it to last up to twice as long as traditional neurotoxins, often around 6 months or more. It’s an excellent choice for those who prefer fewer treatment visits per year or who want sustained smoothness between maintenance appointments.
Best for: Patients seeking longer-lasting results.
Onset: 1–2 days in many cases.
Duration: 6+ months.
Highlights: Extended longevity; innovative peptide stabilizer instead of human serum albumin.
Jeuveau®
Nicknamed “Newtox,” Jeuveau (prabotulinumtoxinA) was specifically developed for cosmetic use. Its formulation is slightly different from Botox’s, but its effect is very similar, many patients find it gives a soft, youthful look with a slightly faster onset. Jeuveau is often popular among younger clients looking for early prevention or a budget-friendly alternative.
Best for: Younger patients or those who prefer a fresher, slightly faster-acting option.
Onset: 2–5 days.
Duration: 3–4 months.
Highlights: Designed purely for aesthetics; often competitively priced.
Dysport®
Dysport (abobotulinumtoxinA) tends to diffuse more readily in the tissue, making it well-suited for larger treatment areas such as the forehead or when softer blending is desired. Some clients also report that Dysport starts working a bit faster than Botox — sometimes within just two to three days.
Best for: Broad forehead lines or when subtle, blended results are preferred.
Onset: 2–3 days.
Duration: 3–4 months.
Highlights: Quick onset and slightly wider spread; ideal for certain facial zones.
Choosing the Right One for You
While all five products deliver excellent wrinkle-relaxing results, the best choice depends on your anatomy, goals, and lifestyle. At LivingYoung Center, our experienced injectors will assess your facial expressions, muscle strength, and past experience with neurotoxins to design a plan that fits you perfectly.
Some patients prefer the longevity of Daxxify, others appreciate the purity of Xeomin, while many stay loyal to the proven results of Botox. The great news is that switching between products is entirely safe, and sometimes recommended to fine-tune your outcome over time.
Our philosophy is simple: use the right product, in the right dose, for the right person. That’s how we ensure your results look refreshed, natural, and unmistakably you — never frozen or overdone.